This free CME activity is exclusively available to members of the American College of Osteopathic Obstetricians and Gynecologists
Release Date: December 22, 2025
Expiration Date: December 31, 2026
Endometrial cancer remains the most common gynecologic malignancy in the United States, with both incidence and mortality continuing to rise. Despite a well-established diagnostic pathway and the frequent presence of early warning symptoms, significant disparities in outcomes persist, particularly among Black women. This article reviews current epidemiology, risk factors, and presenting features of endometrial cancer, emphasizing the importance of prompt evaluation of abnormal uterine bleeding. It also outlines contemporary diagnostic strategies and evolving treatment paradigms, including the integration of molecular classification, fertility-sparing approaches, and advances in systemic therapy. Recent progress in immunotherapy and targeted treatments has expanded options for advanced and recurrent disease. Early recognition, equitable diagnostic evaluation, and individualized, genomics-informed care remain central to improving outcomes for all patients with endometrial cancer.
Gynecologic Oncologist at City of Hope
Dr. Natalie Godbee graduated from Howard University in Washington D.C., where she received a Bachelor of Science in mathematics. She went on to earn her Doctor of Osteopathic Medicine from Philadelphia College of Osteopathic Medicine-Georgia Campus in Suwanee. She was then Chief Resident and completed an obstetrics and gynecology residency at Henry Ford Macomb Hospital in Clinton Township, Michigan. Dr. Godbee completed a fellowship in gynecologic oncology at Wellspan York Hospital in York, Pennsylvania. She currently works at City of Hope in Atlanta, GA.
ACOOG requires each planner and presenter to identify all conflicts of interest, and mitigates risk of bias using a series of strategies for relevant conflicts. Unless otherwise noted below, the ACOOG, ACOOG staff and planners for this activity have no relevant financial relationships to disclose.Dr. Godbee has no relevant financial relationships with ineligible companies to disclose.
The American College of Osteopathic Obstetricians and Gynecologists is accredited by the American Osteopathic Association to provide osteopathic continuing medical education for physicians.
The American College of Osteopathic Obstetricians and Gynecologists is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The American College of Osteopathic Obstetricians and Gynecologists designates this program for a maximum of 0.5 AOA Category 1-B credits and will report CME and specialty credits commensurate with the extent of the physician’s participation in this activity.The American College of Osteopathic Obstetricians and Gynecologists designates this enduring activity for a maximum of 0.5 AMA PRA Category 1 Credits™.
Physicians should only claim credit commensurate with the extent of their participation in the activity.
The American College of Osteopathic Obstetricians and Gynecologists designates this activity for Category 1 College Cognate Credits. Maximum Cognates are equal to the number of maximum AMA PRA Category 1 CreditsTM . A reciprocity agreement with the AMA exists that allows AMA PRA Category 1 CreditsTM to be equivalent to ACOG Cognate Credits.
The American Academy of Nurse Practitioners Certification Board (AANPCB) recognizes activities approved for Category 1-A credit through the American Osteopathic Association and Category 1 AMA PRA Category 1 Credits™ as providing advanced practice CE content hours for applicants seeking renewal through continuing education credit.
The National Commission on Certification of Physician Assistants (NCCPA) recognizes activities approved for Category 1-A credit through the American Osteopathic Association and AMA PRA Category 1 Credits™ as Regular Category 1 CME for national certification maintenance.
The Certificate Maintenance Program of the American Midwifery Certification Board accepts AMA PRA Category 1 Credits™ to satisfy its contact hours requirement.
All NPs, PAs, CNMs and other health professionals participating in this activity will receive a certificate of completion commensurate with the extent of their participation in the activity. ACOOG strongly recommends all non-physician health professionals check with their certification/licensing organizations to confirm credit reciprocity.
An internet-connected device (computer or mobile) with high-speed access is required. Compatible with most popular web browsers. JavaScript and cookies must be enabled.
Participants must complete the pre-test, read the text-based content, pass the post-test (70% or greater), complete the activity evaluation, and claim credit.
This activity is not commercially supported.
This activity is for educational purposes only, offered by ACOOG. Physicians must rely on their medical knowledge, experience, and patient relationships for clinical decisions.
ChatGPT and Google Gemini aided in the editorial review of the front matter and drafting assessment questions.
Registrants with grievances should submit a written grievance to ACOOG, PO Box 17598, Fort Worth, TX 76102.
This activity complies with ACOOG’s privacy policies.
Data collected as part of this activity may be analyzed as part of educational research to study the effectiveness of educational interventions on health care, population health, health care providers and others, or to identify additional needs and gaps for future interventions.
Refunds are not available for this educational product.
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