Recurrent pregnancy loss (RPL), defined as two or more pregnancy losses before 20 weeks' gestation, affects 1–5% of couples and presents complex clinical and emotional challenges. Up to half of RPL cases remain unexplained, heightening patient distress and diagnostic uncertainty. Patients and families often lack comprehensive support, while obstetricians face difficulties in diagnosis, communication, and resource limitations. Medical education insufficiently prepares providers for these challenges.
This virtual symposium provides targeted sessions focused on improving clinical knowledge, enhancing empathetic communication, promoting provider well-being, and advancing integrated, interprofessional care models to better support patients, families, and clinicians managing RPL.
Brad Irving, DO
Program Chair
American College of Osteopathic Obstetricians and Gynecologists
Session: Setting the Foundation
Anthony Sciscione, DO
Maternal–Fetal Medicine
Managing Partner, Delaware Center for Maternal-Fetal Medicine, Christiana Care Health System, Newark, DE
Session: Real-World RPL Challenges
Joanne Stone, MD
Director, Rainbow Clinic
Professor & System Chair of Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York, NY
Session: Rainbow Clinic Approach
Drucilla Roberts, MD
Placental Pathology
Pathologist, Massachusetts General Hospital; Subspecialty Head, Obstetric and Perinatal Pathology; Associate Professor of Pathology, Harvard Medical School, Boston, MA
Session: Modern Placental Pathology
Gregory Piazza, MD
Thrombosis Medicine
Associate Professor of Medicine, Harvard Medical School; Faculty, Division of Cardiovascular Medicine at Brigham and Women's Hospital, Boston, MA
Session: Thrombosis in Pregnancy Loss
Charles Lockwood, MD
Maternal–Fetal Medicine
Executive Vice President, USF Health Dean, USF Health Morsani College of Medicine, University of South Florida, Tampa, FL
Session: Anticardiolipin Syndrome
Mili Thakur, MD, FACOG, FACMG
Reproductive Genetics
Founder, Genome Alley; Clinical Adjunct Assistant Professor, Department of Ob/Gyn and Reproductive Biology, College of Human Medicine, Michigan State University, Grand Rapids, MI
Session: Chromosome Testing Revolution
Winifred Mak, MD, PhD
Reproductive Medicine
Associate Professor of Obstetrics & Gynecology, Reproductive Endocrinology and Infertility, University of Texas Health Science San Antonio; Associate Professor, Dell Medical School, Austin, TX
Session: Future Directions
Loree Johnson, PhD, LFMT
Family & Marriage Therapy
Reproductive Mental Health Specialist in private practice.
Session: Mental Health in Reproductive Care
Megan Hanson
Patient & Advocate
Co-Founder and Executive Director, Recurrent Pregnancy Loss Association (RPLA)
Session: Patient Perspective
Avital Kedem, MSW, LCSW
Bereavement & Support
Bereavement Social Worker, Rainbow Clinic, Mount Sinai, New York, NY
Session: Mental Health in Reproductive Care
Ronald Librizzi, DO, FACOOG — Distinguished Fellow
Thank you to Dr. Ronald Librizzi for expertise and leadership that helped shape this program and ensure clinical rigor.
Recurrent Pregnancy Loss Association — Patient Advocacy Partner
We appreciate the Association's advocacy and patient-centered resources that keep this work anchored in real needs.
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Beyond the Statistics: Real-World RPL Challenges
Anthony Sciscione, DO & Megan Hanson
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After the Storm: The Rainbow Clinic Approach
Joanne Stone, MD
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Decoding the Placenta: Modern Pathology
Drucilla Roberts, MD
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When Blood Betrays: Thrombosis in Pregnancy Loss
Gregory Piazza, MD
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When Antibodies Attack: Antiphospholipid Syndrome
Charles Lockwood, MD
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Genetic Testing for Recurrent Pregnancy Loss
Mili Thakur, MD
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Patient Perspectives & Future Directions
Winifred Mak, MD, PhD
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Mental Health in Reproductive Care
Winifred Mak, MD, PhD; Loree Johnson, PhD, LFMT; Avital Kedem, MSW, LCSW; and Megan Hanson
ACOOG requires each planner and author to identify all financial relationships with ineligible companies and mitigates risk of bias using a series of strategies for relevant relationships. Unless otherwise noted below, ACOOG, ACOOG staff, planners, and faculty for this activity have no relevant financial relationships to disclose.
The following presenters reported no relevant financial relationships
- Brad Irving, DO
- Anthony Sciscione, DO
- Joanne Stone, MD
- Drucilla Roberts, MD
- Charles Lockwood, MD
- Winifred Mak, MD, PhD
- Loree Johnson, PhD, LFMT
- Megan Hanson
- Avital Kedem, MSW, LCSW
The following presenters reported relevant financial relationships. All relationships have been mitigated
Gregory Piazza, MD
Dr. Piazza has disclosed he has received research funding from BMS/Pfizer, Janssen, Alexion, Bayer, Amgen, BSC, Esperion, and Regeneron, and serves in an advisory role for Amgen, Thrombolex, BMS/Pfizer, BMS, and Janssen. These relationships have been mitigated.
Mili Thakur, MD, FACOG, FACMG
Dr. Thakur is a non-CME speaker for Natera, Juniper Genomics, and PGT Labs. This relationship has been mitigated.
Those participating in this activity will receive information that should allow them to:
- Define recurrent pregnancy loss and identify appropriate diagnostic evaluation protocols.
- Implement evidence-based mental health support strategies for patients experiencing RPL.
- Interpret placental pathology reports to guide clinical decision-making.
- Apply current genetic testing methodologies in the evaluation of pregnancy loss.
- Recognize and manage thrombophilias and antiphospholipid syndrome in pregnancy.
- Integrate current research findings into clinical practice for RPL management.
Accreditation and Credit Designation
CME Accreditation
The American College of Osteopathic Obstetricians and Gynecologists is accredited by the American Osteopathic Association to provide osteopathic continuing medical education for physicians.
The American College of Osteopathic Obstetricians and Gynecologists is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
CME Credit Designation
This program qualifies for 7 AOA Category 1-A credit under an exemption approved by the Bureau of Osteopathic Education of the American Osteopathic Association.
The American College of Osteopathic Obstetricians and Gynecologists designates this enduring online activity for a maximum of 7 AMA PRA Category 1 Credits™.
Physicians should only claim credit commensurate with the extent of their participation in the activity.
ACOG Cognate Credit(s)
The American College of Osteopathic Obstetricians and Gynecologists designates this activity for Category 1 College Cognate Credits equal to the number of AMA PRA Category 1 Credits™ claimed by the participant. ACOG recognizes AMA PRA Category 1 Credits™ to be equivalent to ACOG Cognate Credits.
NPs, PAs & CNMs
The American Academy of Nurse Practitioners Certification Board (AANPCB) recognizes activities approved for Category 1-A credit through the American Osteopathic Association and Category 1 AMA PRA Category 1 Credits™ as providing advanced practice CE content hours for applicants seeking renewal through continuing education credit.
The National Commission on Certification of Physician Assistants (NCCPA) recognizes activities approved for Category 1-A credit through the American Osteopathic Association and AMA PRA Category 1 Credits™ as Regular Category 1 CME for national certification maintenance.
The Certificate Maintenance Program of the American Midwifery Certification Board accepts AMA PRA Category 1 Credits™ to satisfy its contact hours requirement.
All NPs, PAs, CNMs and other health professionals participating in this activity will receive a certificate of completion commensurate with the extent of their participation in the activity. ACOOG strongly recommends all non-physician health professionals check with their certification/licensing organizations to confirm credit reciprocity.
This activity is not commercially supported.
Format and System Requirements
This is an on-demand (enduring) activity. An internet-connected device (computer or mobile) with high-speed access is required. Compatible with most popular web browsers. JavaScript and cookies must be enabled. If you are experiencing technical issues, please update your browser and clear your browsing history, cookies, and cache.
Requirements for Successful Completion
- Register for and participate in the activity, viewing each session.
- Complete the post-test.
- Complete the activity evaluation.
- Claim credit.
Certificates are available in the ACOOG learning center (under Transcripts) after completion.
Medical Judgement
This activity is for educational purposes only, offered by ACOOG. Physicians must rely on their medical knowledge, experience, and patient relationships for clinical decisions.
Use of Artificial Intelligence
The closed captions and summaries provided in this content are automatically generated by artificial intelligence (AI). While AI can enhance accessibility and comprehension, it is not infallible and may produce errors. Please keep this in mind as you engage with and apply the content.
Grievances: Any registrant finding evidence that the continuing medical education activity presented is inappropriate with regard to facilities, materials, content, or who observes any unacceptable promotion by a commercial interest may submit a grievance in writing to ACOOG, PO Box 17598, Fort Worth, TX 76102. Unresolved issues regarding this activity will require a formal written complaint to the AOA Division of CME, 142 East Ontario Street, Chicago, IL 60611.
Privacy policy: This activity complies with ACOOG’s privacy policies.
Data use: Data collected as part of this activity may be analyzed as part of educational research to study the effectiveness of educational interventions on health care, population health, health care providers and others, or to identify additional needs and gaps for future interventions.
Refunds: Refunds are not available for this educational product.